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Avapro also known as irbesartan is known to potentially interact when it is taken together with other medicines. There may be negative interactions when Avapro is taken along with potassium-sparing diuretics, diuretics, or potassium supplements. The body may metabolize these medicines differently than in a manner in which it was intended to, due to interactions with Avapro. This may result in excessive levels of potassium in the blood leading to hypotension or low blood pressure.
Some of the drug interactions with Avapro include:
Interaction of specific drugs with Avapro:
Diuretics: When Avapro is taken along with a diuretic, then the blood pressure may go down to dangerous levels. This normally occurs initially, when a course of Avapro is started. To avoid this, you healthcare provider might alter the dosage of either medicine and put you on a low dose of Avapro and also monitor you closely.
Potassium supplements: If you are on potassium supplements then Avapro may cause interactions and the levels of potassium in the blood may reach dangerously high levels and lead to a lot of problems. You must discuss this in detail with your healthcare provider and check to see if potassium supplements could be used along with Avapro in a particular situation.
Potassium-Sparing Diuretics: When Avapro is taken along with potassium-sparing diuretics then the body tends to metabolize them very differently than the way it was intended to and this will cause an increase in the potassium levels in the blood. Hence, it is important to discuss with your healthcare provider as the situation needs to be monitored closely.
Use of Avapro during pregnancy:Avapro is not recommended during pregnancy as it is known to pose risks for the unborn fetus. Pregnancy category C and D classifications have been given to Avapro and both of it means there is clear evidence of risks to the unborn fetus. Pregnancy category C means that there were side effects in studies conducted on animals and Pregnancy category D means that there is evidence of risks to the unborn fetus in human studies as well. There are many complications that may arise due to the use of Avapro and these complications may include kidney failure, developmental problems, facial deformities, or even loss of life.avapro 150 mg
Healthcare providers earlier believed that Avapro caused problems when it was taken either during the second or third trimester of pregnancy, but that was sometime before 2006. But all of that changed when there was a study conducted by the research team at Vanderbilt University, the results of which was published in the New England Journal of Medicine in June 2006.